SCHEMBL28020004

SCHEMBL28020004

O=C1COc2cc(F)ccc2C1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 5/20 0.39
NOTUM Q6P988 1/20 0.36
FABP6 P51161 1/20 0.36
CYP1A2 P05177 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPK14 Q16539 4/20 0.35
RIPK1 Q13546 1/20 0.35
ACHE P22303 1/20 0.35
PARP1 P09874 1/20 0.35
PARP10 Q53GL7 1/20 0.35
AKR1B10 O60218 1/20 0.35
MAPT P10636 1/20 0.35
AKR1A1 P14550 1/20 0.35
AKR1B1 P15121 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28030845 0.85 NR3C2 (0.40) NR3C2NOTUMFABP6CYP1A2KDM4E
Ammonia Solution, Strong SCHEMBL6506701 0.78 NOTUM (0.41) NR3C2NOTUMKDM4EALDH1A1GAA
SCHEMBL2812418 0.78 BLM (0.41) CYP1A2L3MBTL1PARP1PARP10MAPT
SCHEMBL13156965 0.78 MAPT (0.44) CYP1A2KDM4EALDH1A1GAAMAPK14
SCHEMBL12431219 0.78 AHR (0.41) NOTUMCYP1A2KDM4EMAPK14PARP1
SCHEMBL18983714 0.78 DRD2 (0.46) ALDH1A1MAPTMAOAMAOB
Hydrochloric Acid SCHEMBL10839310 0.76 NOTUM (0.40) NR3C2NOTUMKDM4EALDH1A1GAA
SCHEMBL10966821 0.75 FABP6 (0.47) NR3C2NOTUMFABP6CYP1A2KDM4E
SCHEMBL18998227 0.75 CYP1A2 (0.33) CYP1A2
SCHEMBL30450885 0.74 CYP1A2 (0.54) CYP1A2ALDH1A1MAPTMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829576-A Preparation method of 7-fluoropyran derivatives Hunan huateng pharmaceutical co ltd 2015-08-12 CN disclosed