Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | UGCG | Q16739 | 1/20 | 0.44 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 7/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508803 | 0.83 | ESR1 (0.46) | L3MBTL1TDP1AGXTGBA1UGCG | |
| SCHEMBL5574984 | 0.82 | IDO1 (0.54) | IDO1AGXTESR1CA1CA2 | |
| SCHEMBL6507918 | 0.82 | ESR1 (0.48) | L3MBTL1TDP1GBA1UGCGGBA2 | |
| SCHEMBL16614396 | 0.81 | L3MBTL1 (0.67) | L3MBTL1TDP1IDO1AGXTGBA1 | |
| SCHEMBL6496291 | 0.80 | L3MBTL1 (0.65) | L3MBTL1TDP1IDO1AGXTGBA1 | |
| SCHEMBL9021156 | 0.80 | L3MBTL1 (0.65) | L3MBTL1TDP1IDO1AGXTGBA1 | |
| SCHEMBL1355360 | 0.80 | L3MBTL1 (0.65) | L3MBTL1TDP1IDO1AGXTGBA1 | |
| SCHEMBL16727734 | 0.80 | L3MBTL1 (0.65) | L3MBTL1TDP1IDO1AGXTGBA1 | |
| SCHEMBL6551488 | 0.80 | L3MBTL1 (0.65) | L3MBTL1TDP1IDO1AGXTGBA1 | |
| SCHEMBL9021153 | 0.80 | L3MBTL1 (0.65) | L3MBTL1TDP1IDO1AGXTGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123670-A2 | CRYSTALLINE FORM OF A SUBSTITUTED PYRROLIDINE COMPOUND | THERAVANCE, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| WO-2005100329-A1 | NOVEL PROTECTING REAGENTS, PROTECTING GROUPS AND METHODS OF FORMING AND USING THE SAME | THE UNIVERSITY OF MISSISSIPI (US) | 2005-10-27 | — | — | WO | disclosed |