Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | UGCG | Q16739 | 14/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 14/20 | 0.36 |
| ▸ | GBA1 | P04062 | 13/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | LCT | P09848 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508803 | 0.85 | ESR1 (0.46) | ESR1L3MBTL1TDP1UGCGGBA2 | |
| SCHEMBL6506706 | 0.82 | L3MBTL1 (0.61) | ESR1L3MBTL1TDP1UGCGGBA2 | |
| SCHEMBL6509740 | 0.81 | ESR1 (0.43) | ESR1L3MBTL1TDP1HRH3PLA2G4B | |
| SCHEMBL6512248 | 0.81 | GBA1 (0.49) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL21169170 | 0.81 | GBA1 (0.49) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL6508614 | 0.81 | ESR1 (0.42) | ESR1L3MBTL1TDP1UGCGGBA2 | |
| SCHEMBL9278188 | 0.79 | GBA1 (0.47) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL9233338 | 0.79 | TSHR (0.48) | L3MBTL1TDP1PLA2G4B | |
| SCHEMBL6530577 | 0.78 | ESR1 (0.40) | ESR1L3MBTL1TDP1HRH3 | |
| SCHEMBL6551488 | 0.78 | L3MBTL1 (0.65) | L3MBTL1TDP1UGCGGBA2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100329-A1 | NOVEL PROTECTING REAGENTS, PROTECTING GROUPS AND METHODS OF FORMING AND USING THE SAME | THE UNIVERSITY OF MISSISSIPI (US) | 2005-10-27 | — | — | WO | disclosed |