⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19730712 | 0.90 | — | — | |
| SCHEMBL20921954 | 0.70 | — | — | |
| SCHEMBL5609934 | 0.63 | — | — | |
| SCHEMBL3514323 | 0.60 | — | — | |
| SCHEMBL620964 | 0.60 | — | — | |
| SCHEMBL1578751 | 0.60 | — | — | |
| SCHEMBL1265060 | 0.60 | — | — | |
| SCHEMBL22280384 | 0.60 | — | — | |
| SCHEMBL6506759 | 0.60 | — | — | |
| SCHEMBL446743 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | claimed |
| JP-2088578-A | — | — | None | — | — | JP | disclosed |
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | disclosed |
| JP-H0288578-A | PRODUCTION OR CARBAPENEM COMPOUND | LEDERLE JAPAN LTD | 1990-03-28 | — | — | JP | disclosed |