Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506763 | 1.00 | KIFC1 (0.47) | KIFC1PTPN1PTPN11ITGB1ITGA4 | |
| SCHEMBL4831640 | 0.99 | KIFC1 (0.48) | KIFC1PTPN1PTPN11ITGB1ITGA4 | |
| SCHEMBL3999740 | 0.99 | KIFC1 (0.48) | KIFC1PTPN1PTPN11ITGB1ITGA4 | |
| SCHEMBL3998693 | 0.92 | PTPN1 (0.43) | KIFC1PTPN1PTPN11ITGB1ITGA4 | |
| SCHEMBL4829602 | 0.92 | ITGA4 (0.44) | KIFC1PTPN1PTPN11ITGB1ITGA4 | |
| SCHEMBL4829606 | 0.92 | ITGA4 (0.44) | KIFC1PTPN1PTPN11ITGB1ITGA4 | |
| SCHEMBL3995232 | 0.92 | ITGA4 (0.43) | KIFC1PTPN11ITGB1ITGA4ITGB7 | |
| SCHEMBL3995215 | 0.91 | PTPN11 (0.46) | KIFC1PTPN1PTPN11ITGB1ITGA4 | |
| SCHEMBL6506765 | 0.90 | PTPN1 (0.41) | KIFC1PTPN1PTPN11ITGB1ITGA4 | |
| SCHEMBL3991617 | 0.90 | ITGA4 (0.48) | PTPN1PTPN11ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014534-A1 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | TRANSTECH PHARMA, INC. (US) | 2005-02-17 | — | — | WO | disclosed |