Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 11/20 | 0.46 |
| ▸ | THRB | P10828 | 11/20 | 0.46 |
| ▸ | RARB | P10826 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5402713 | 0.94 | THRA (0.42) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL6501573 | 0.93 | THRA (0.44) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL6508362 | 0.90 | RARB (0.48) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL15894876 | 0.89 | THRA (0.46) | THRATHRBHAO1HSD17B3 | |
| SCHEMBL6502423 | 0.88 | RARB (0.45) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL7620878 | 0.88 | THRA (0.46) | THRATHRBHAO1HSD17B3 | |
| SCHEMBL8498944 | 0.87 | TNNC1 (0.45) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL8496902 | 0.87 | TNNC1 (0.45) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL8499864 | 0.87 | TNNC1 (0.45) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL5403214 | 0.86 | RARB (0.48) | RARBMEN1ALDH1A1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |