Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.45 |
| ▸ | F10 | P00742 | 10/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.45 |
| ▸ | PLG | P00747 | 9/20 | 0.45 |
| ▸ | PLAU | P00749 | 9/20 | 0.45 |
| ▸ | PLAT | P00750 | 8/20 | 0.45 |
| ▸ | HPN | P05981 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510692 | 0.92 | F2 (0.47) | F2F10PRSS1PLGPLAU | |
| SCHEMBL6506820 | 0.91 | F2 (0.44) | F2F10PRSS1PLGPLAU | |
| SCHEMBL6506693 | 0.84 | HDAC1 (0.48) | F2F10PRSS1PLAUHDAC6 | |
| SCHEMBL6510661 | 0.84 | F2 (0.46) | F2F10PRSS1PLGPLAU | |
| SCHEMBL6510570 | 0.84 | F2 (0.55) | F2F10PRSS1PLGPLAU | |
| SCHEMBL5390642 | 0.83 | PLAU (0.57) | F2F10PRSS1PLGPLAU | |
| SCHEMBL6505463 | 0.80 | HDAC6 (0.45) | F2F10PRSS1PLGPLAU | |
| SCHEMBL6511666 | 0.80 | HDAC6 (0.42) | F2F10PRSS1PLGPLAU | |
| SCHEMBL6511681 | 0.80 | HDAC1 (0.44) | F2F10PRSS1PLGPLAU | |
| SCHEMBL6510699 | 0.79 | HDAC1 (0.49) | F2F10PRSS1PLAUHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | BOYKIN DAVID W (US) | 2005-07-07 | — | — | US | claimed |
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | BOYKIN DAVID W (US) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | DDT, DDC, DARS1 | F2 2666/4885F10 3872/4885PRSS1 2474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.