SCHEMBL6507188

SCHEMBL6507188

CC(O)CC=O.CCC(=O)C(C)(C)[C@@H](O)CC(C)=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4806982 0.74 PGD (0.43) ALDH1A1TDP1
SCHEMBL4807998 0.74 PGD (0.43) ALDH1A1TDP1
SCHEMBL34475233 0.72
Acetone SCHEMBL1147312 0.71 ALDH1A1 (0.34) ALDH1A1TDP1
Acetic Acid SCHEMBL2728218 0.69 FFAR3 (0.37) ALDH1A1TDP1
Propane SCHEMBL4876307 0.69
SCHEMBL9027 0.69
SCHEMBL10679392 0.69 TSHR (0.39) ALDH1A1TDP1
SCHEMBL9026 0.69
SCHEMBL3475223 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005054429-A2 SYNTHESIS OF THE C1-C6 KETO-ACID SYNTHON OF THE EPOTHILONES THE UNIVERSITY OF MISSISSIPPI (US) 2005-06-16 WO disclosed