Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23368101 | 1.00 | MEN1 (0.54) | MEN1KMT2ALMNANPC1PKM | |
| SCHEMBL3892343 | 1.00 | MEN1 (0.54) | MEN1KMT2ALMNANPC1PKM | |
| Hydrochloric Acid SCHEMBL1503717 | 0.98 | MEN1 (0.53) | MEN1KMT2ALMNANPC1PKM | |
| SCHEMBL16980498 | 0.85 | RAB9A (0.51) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL6555717 | 0.84 | CA12 (0.54) | MEN1KMT2ALMNAMAPTL3MBTL1 | |
| SCHEMBL6555720 | 0.84 | CA12 (0.54) | MEN1KMT2ALMNAMAPTL3MBTL1 | |
| SCHEMBL4423243 | 0.83 | LMNA (0.49) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL4423246 | 0.83 | LMNA (0.49) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL28522244 | 0.82 | MEN1 (0.50) | MEN1KMT2ALMNANPC1PKM | |
| SCHEMBL19707799 | 0.82 | KMT2A (0.48) | MEN1KMT2ALMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058831-A1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005047253-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2005-05-26 | — | — | WO | disclosed |
| US-5264436-A | Alpha-adrenoceptors antagonist, hypotensive agents or antidiabetic agents | BEECHAM GROUP P.L.C. (GB) | 1993-11-23 | — | — | US | disclosed |
| EP-0275639-B1 | N-SUBSTITUTED CYCLIC AMIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1992-07-15 | — | — | EP | disclosed |
| EP-0238753-B1 | N-SUBSTITUTED CONDENSED POLYMETHYLENE IMINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-01-15 | — | — | EP | disclosed |
| US-5077299-A | Glaucoma, antidepressants, anticoagulants, hypotensive agents | BEECHAM GROUP P.L.C. (GB) | 1991-12-31 | — | — | US | disclosed |
| US-4959374-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS, GLAUCOMA, HYPERGLYCEMIC AGENTS, ANTIDEPRESSANTS | BEECHAM GROUP P.L.C. (GB) | 1990-09-25 | — | — | US | disclosed |
| US-4918083-A | 4,5 Dihydroimidazole compounds which have useful pharmaceutical utility | BEECHAM GROUP P.L.C. (GB) | 1990-04-17 | — | — | US | disclosed |
| EP-0131174-B1 | SUBSTITUTED PHENYLGLYCINE DERIVATIVES OF BETA-LACTAM ANTIBIOTICS | BEECHAM GROUP PLC (GB) | 1989-09-13 | — | — | EP | disclosed |
| US-4863946-A | HYPOGLYCEMIC AND HYPOTENSIVE AGENTS | BEECHAM GROUP PLC (GB) | 1989-09-05 | — | — | US | disclosed |
| EP-0275639-A1 | N-substituted cyclic amides, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-07-27 | — | — | EP | disclosed |
| EP-0250528-A1 | OXAZOLE DERIVATIVES AND THEIR USE AS ANTI-HYPERGLYCAEMIC | BEECHAM GROUP PLC (GB) | 1988-01-07 | — | — | EP | disclosed |
| EP-0238753-A1 | N-substituted condensed polymethylene imine derivatives | BEECHAM GROUP PLC (GB) | 1987-09-30 | — | — | EP | disclosed |
| US-4684639-A | Antibacterial penicillins and cephalosporins | BEECHAM GROUP (GB) | 1987-08-04 | — | — | US | disclosed |
| WO-1987003807-A1 | OXAZOLE DERIVATIVES AND THEIR USE AS ANTI-HYPERGLYCAEMIC | BEECHAM GROUP P.L.C. (GB) | 1987-07-02 | — | — | WO | disclosed |
| EP-0112685-B1 | COMPOUNDS CONTAINING BETA-LACTAMS | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | disclosed |
| EP-0131174-A1 | Substituted phenylglycine derivatives of beta-lactam antibiotics | BEECHAM GROUP PLC (GB) | 1985-01-16 | — | — | EP | disclosed |
| EP-0112685-A1 | Compounds containing beta-lactams | BEECHAM GROUP PLC (GB) | 1984-07-04 | — | — | EP | disclosed |