Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 8/20 | 0.62 |
| ▸ | TACR2 | P21452 | 7/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.62 |
| ▸ | TRPV4 | Q9HBA0 | 13/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5945397 | 0.89 | TACR3 (0.77) | TACR3TACR2OPRM1TRPV4KCNH2 | |
| SCHEMBL6506812 | 0.87 | TRPV4 (0.58) | TACR3TACR2OPRM1TRPV4KCNH2 | |
| SCHEMBL5732536 | 0.81 | TACR2 (0.71) | TACR3TACR2OPRM1TRPV4KCNH2 | |
| SCHEMBL7225413 | 0.76 | TRPV4 (0.67) | TACR3TACR2OPRM1TRPV4 | |
| SCHEMBL5945344 | 0.76 | TRPV4 (0.80) | TACR3TACR2OPRM1TRPV4KCNH2 | |
| SCHEMBL2373330 | 0.76 | TRPV4 (0.72) | TACR3TACR2OPRM1TRPV4KCNH2 | |
| Hydrochloric Acid SCHEMBL5733490 | 0.75 | TRPV4 (0.71) | TACR3TACR2OPRM1TRPV4KCNH2 | |
| SCHEMBL6533888 | 0.75 | TRPV4 (0.54) | TACR3TACR2OPRM1TRPV4KCNH2 | |
| SCHEMBL5203642 | 0.75 | TRPV4 (0.73) | TACR3TACR2OPRM1TRPV4KCNH2 | |
| SCHEMBL6428018 | 0.74 | TRPV4 (0.70) | TACR3TACR2OPRM1TRPV4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016878-A2 | METHODS FOR THE PREPARATION OF 5-FLUORO-PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005000845-A2 | BICYCLIC DERIVATIVES AS NK-1 AND NK-2 ANTAGONISTS | NIKEM RESEARCH S.R.L. (IT) | 2005-01-06 | — | — | WO | claimed |
| CN-101531695-A | Method for synthesizing fluoro-oligonucleotide for preparing siRNA | ZHENGZHOU RUISAI TECHNOLOGY AN | 2009-09-16 | — | — | CN | disclosed |
| WO-2005000845-A2 | BICYCLIC DERIVATIVES AS NK-1 AND NK-2 ANTAGONISTS | NIKEM RESEARCH S.R.L. (IT) | 2005-01-06 | — | — | WO | disclosed |