Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507843 | 1.00 | HDAC1 (0.54) | HDAC1HDAC3HDAC2HDAC8NCOR2 | |
| SCHEMBL6508468 | 0.89 | MEP1B (0.47) | HDAC1HDAC3HDAC2HDAC8NCOR2 | |
| SCHEMBL6508462 | 0.89 | MEP1B (0.47) | HDAC1HDAC3HDAC2HDAC8NCOR2 | |
| SCHEMBL5146175 | 0.87 | HDAC3 (0.62) | HDAC1HDAC3HDAC2HDAC8NCOR2 | |
| Hydrochloric Acid SCHEMBL28989572 | 0.85 | HDAC3 (0.60) | HDAC1HDAC3HDAC2HDAC8NCOR2 | |
| Ammonia Solution, Strong SCHEMBL27489179 | 0.85 | HDAC3 (0.60) | HDAC1HDAC3HDAC2HDAC8NCOR2 | |
| SCHEMBL6511912 | 0.84 | HTT (0.45) | HDAC1HDAC3HDAC2HDAC8NCOR2 | |
| SCHEMBL6518342 | 0.84 | HDAC4 (0.49) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL6511915 | 0.84 | HTT (0.45) | HDAC1HDAC3HDAC2HDAC8NCOR2 | |
| SCHEMBL6518341 | 0.84 | HDAC4 (0.49) | HDAC1HDAC3HDAC2HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |