Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508462 | 1.00 | MEP1B (0.47) | MEP1BHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6507841 | 0.89 | HDAC1 (0.54) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6507843 | 0.89 | HDAC1 (0.54) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6513388 | 0.88 | MEP1B (0.46) | MEP1BHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6511915 | 0.84 | HTT (0.45) | MEP1BHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6511912 | 0.84 | HTT (0.45) | MEP1BHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6515378 | 0.84 | FFAR1 (0.52) | MEP1B | |
| SCHEMBL6512357 | 0.83 | TAS2R14 (0.43) | MEP1BHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6512683 | 0.81 | MEP1B (0.46) | MEP1BTAS2R14EGFRNR1H4L3MBTL1 | |
| SCHEMBL6510768 | 0.80 | ALDH1A1 (0.43) | MEP1BHDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |