SCHEMBL6507908

SCHEMBL6507908

O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(SC(F)(F)F)cc1Cl

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
MAPT P10636 2/20 0.54
USP2 O75604 1/20 0.54
ALOX15 P16050 1/20 0.54
ATM Q13315 1/20 0.47
POLB P06746 1/20 0.43
TLR7 Q9NYK1 1/20 0.41
PYGL P06737 3/20 0.41
KCNK2 O95069 3/20 0.41
KCNK10 P57789 2/20 0.41
NPC1 O15118 1/20 0.40
MAPK1 P28482 1/20 0.40
RAB9A P51151 1/20 0.40
GAA P10253 1/20 0.39
IL2 P60568 1/20 0.39
PPIA P62937 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6507280 0.95 KMT2A (0.52) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL4141917 0.89 MEN1 (0.51) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL10360662 0.89 KMT2A (0.56) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL6511477 0.89 KMT2A (0.52) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL11336580 0.86 KMT2A (0.52) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL5311613 0.86 MEN1 (0.48) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL6508027 0.86 KMT2A (0.49) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL6505143 0.85 KMT2A (0.48) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL6514824 0.84 MEN1 (0.51) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL6511572 0.81 KMT2A (0.60) MEN1KMT2AMAPTUSP2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-21 US disclosed
EP-1481972-A1 CYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL AGENT Sumitomo Chemical Takeda Agro Company, Limited (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent CNPY2, CNPY3, HAX1 MEN1 2593/4885KMT2A 1362/4885MAPT 4484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.