SCHEMBL6511477

SCHEMBL6511477

O=C(NC(=O)c1c(F)cccc1Cl)Nc1ccc(SC(F)(F)F)cc1F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
MAPT P10636 2/20 0.48
USP2 O75604 1/20 0.48
ALOX15 P16050 1/20 0.48
GAA P10253 5/20 0.47
TLR7 Q9NYK1 2/20 0.47
LMNA P02545 1/20 0.47
PKM P14618 1/20 0.47
PPIA P62937 1/20 0.45
TLR8 Q9NR97 2/20 0.44
ATM Q13315 1/20 0.43
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
JAK2 O60674 1/20 0.42
JAK1 P23458 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6507280 0.93 KMT2A (0.52) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL4141917 0.92 MEN1 (0.51) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6506821 0.91 KMT2A (0.50) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6508537 0.91 KMT2A (0.50) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL11336580 0.91 KMT2A (0.52) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6508027 0.90 KMT2A (0.49) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL5314170 0.89 KMT2A (0.48) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6507908 0.89 MEN1 (0.57) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL11339687 0.85 GAA (0.53) KMT2AMEN1MAPTGAATLR7
SCHEMBL6506002 0.84 TLR7 (0.47) KMT2AMEN1MAPTUSP2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100374427-C Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEM TAKEDA AGRO CO (JP) 2008-03-12 CN disclosed
CN-101108830-A Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEM TAKEDA AGRO CO (JP) 2008-01-23 CN disclosed
CN-101003517-A Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEM TAKEDA AGRO CO (JP) 2007-07-25 CN disclosed
CN-1649850-A Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEM TAKEDA AGRO CO (JP) 2005-08-03 CN disclosed
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-21 US disclosed
EP-1481972-A1 CYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL AGENT Sumitomo Chemical Takeda Agro Company, Limited (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent CNPY2, CNPY3, HAX1 KMT2A 1362/4885MEN1 2593/4885MAPT 4484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.