Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22811928 | 0.94 | THRB (0.40) | THRBTSHRALDH1A1NPSR1CA1 | |
| SCHEMBL22811877 | 0.92 | THRB (0.40) | THRBTSHRALDH1A1NPSR1CA1 | |
| SCHEMBL14962543 | 0.91 | THRB (0.46) | THRBTSHRALDH1A1NPSR1CA1 | |
| SCHEMBL17717373 | 0.88 | THRB (0.33) | THRBALDH1A1NPSR1HTTMEN1 | |
| SCHEMBL8491934 | 0.87 | THRB (0.50) | THRBTSHRALDH1A1NPSR1CA1 | |
| SCHEMBL15131445 | 0.83 | ALDH1A1 (0.33) | THRBALDH1A1NPSR1HTTMEN1 | |
| SCHEMBL17738145 | 0.82 | — | — | |
| SCHEMBL16543373 | 0.82 | THRB (0.36) | THRBTSHR | |
| SCHEMBL17738150 | 0.81 | — | — | |
| SCHEMBL16543374 | 0.81 | THRB (0.35) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8300329-B2 | Optical element assembly and method of manufacturing optical unit | KONICA MINOLTA OPTO, INC. (JP) | 2012-10-30 | — | — | US | disclosed |
| JP-2005008527-A | POLYMERIZABLE ADAMANTANE COMPOUND | TOKUYAMA CORP | 2005-01-13 | — | — | JP | disclosed |