⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10925085 | 0.98 | — | — | |
| SCHEMBL27907862 | 0.83 | — | — | |
| SCHEMBL1043730 | 0.79 | — | — | |
| SCHEMBL27873677 | 0.74 | ALDH1A1 (0.34) | — | |
| SCHEMBL694984 | 0.71 | AKR1B1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL10924546 | 0.70 | AKR1B1 (0.31) | — | |
| SCHEMBL4789244 | 0.67 | — | — | |
| SCHEMBL5533943 | 0.67 | — | — | |
| SCHEMBL1426598 | 0.67 | — | — | |
| SCHEMBL3787492 | 0.66 | CA2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242931-A | Antiischemic agents and cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-07 | — | — | US | claimed |
| JP-2000250-A | — | — | None | — | — | JP | disclosed |
| CN-119097699-A | B7-H4 antibodies and methods of use thereof | 奈斯科尔公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-117177767-A | Proteolytic enzyme mixtures for the treatment of psoriasis | 麦迪伍德有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-116600789-A | Polymeric bile acid ester nanoparticles for inducing tolerance | 耶鲁大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-116348130-A | Method for treating skin cancer | 麦迪伍德有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116322748-A | Compositions and methods for modulating FLRT 3-mediated signal transduction | 奈斯科尔公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-109863168-B | Amylin analogs | 西兰制药公司 | 2023-04-18 | — | — | CN | disclosed |
| WO-2023003497-A1 | COMPOUNDS WITH LYSOSOMOTROPIC AND ANTIVIRAL ACTIVITY | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ВАЛЕНТА-ИНТЕЛЛЕКТ" | 2023-01-26 | — | — | WO | disclosed |
| CN-115298165-A | Tetralin and tetrahydroquinoline compounds as HIF-2 alpha inhibitors | 艾库斯生物科学有限公司 | 2022-11-04 | — | — | CN | disclosed |
| EP-3256468-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-12-20 | — | — | EP | disclosed |
| WO-2016127924-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-08-18 | — | — | WO | disclosed |
| CN-102405039-B | Comprise cosmetics or skin composition and cosmetic treatment method containing the polymer of connecting group | 莱雅公司 | 2016-06-08 | — | — | CN | disclosed |
| EP-2790511-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | Merck Sharp & Dohme Corp. (US) | 2014-10-22 | — | — | EP | disclosed |
| WO-2013090271-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2013-06-20 | — | — | WO | disclosed |
| WO-2005023799-A1 | FUSED BICYCLIC CARBOXAMIDE DERIVATIVES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2005-03-17 | — | — | WO | disclosed |
| EP-0974583-B1 | PHENYLPIPERIDINE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5756553-A | Medical material and process for producing the same | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-05-26 | — | — | US | disclosed |
| JP-H02250-A | TRICYCLIC COMPOUND | KYOWA HAKKO KOGYO CO LTD | 1990-01-05 | — | — | JP | disclosed |
| EP-0188802-A2 | Dibenz (b,e) oxepin derivative and antiallergic agent | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-07-30 | — | — | EP | disclosed |