Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.38 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14004843 | 0.90 | KDM4E (0.42) | LMNASLC2A1KDM4EALDH1A1F2 | |
| SCHEMBL14030942 | 0.88 | SLC2A4 (0.40) | SSTR4SLC2A4SLC2A8SLC2A1KCNQ4 | |
| SCHEMBL4743598 | 0.85 | SLC2A4 (0.40) | SSTR4SLC2A4SLC2A8SLC2A1KCNQ4 | |
| SCHEMBL14004845 | 0.83 | CHRNB2 (0.36) | SSTR4F2 | |
| SCHEMBL5153408 | 0.79 | HDAC3 (0.46) | LMNASMN1; SMN2KDM4EALDH1A1HDAC3 | |
| SCHEMBL6508209 | 0.78 | SSTR4 (0.44) | SSTR4LMNASMN1; SMN2SLC2A4SLC2A8 | |
| SCHEMBL7497944 | 0.75 | SSTR4 (0.40) | SSTR4TP53MAPTKCNQ4KCNQ5 | |
| SCHEMBL4744310 | 0.74 | SSTR4 (0.56) | SSTR4LMNATP53MAPTKCNQ4 | |
| SCHEMBL3899039 | 0.74 | SSTR4 (0.47) | SSTR4LMNASMN1; SMN2TP53MAPT | |
| SCHEMBL2259362 | 0.73 | ROCK1 (0.48) | SSTR4TP53MAPTKCNQ4KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293712-A1 | Benzo[C][2,7]Naphtyridine Derivatives, Methods of Making Thereof and Methods of Use Thereof | WYETH (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293712-A1 | Benzo[C][2,7]Naphtyridine Derivatives, Methods of Making Thereof and Methods of Use Thereof | PDPK1, PDK2, PDK3 | SSTR4 3719/4885LMNA 1422/4885SMN1; SMN2 2665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.