Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | WNT3 | P56703 | 2/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530200 | 0.84 | NOTUM (0.41) | ALDH1A1CA1CA2CA9CA4 | |
| SCHEMBL6508465 | 0.84 | HSD17B10 (0.39) | MEN1KMT2AHSD17B10HRH2HRH1 | |
| SCHEMBL6532944 | 0.81 | ENPP2 (0.38) | — | |
| SCHEMBL6530778 | 0.81 | CA1 (0.48) | ALDH1A1CA1CA2CA9CA4 | |
| SCHEMBL6528013 | 0.81 | NOTUM (0.46) | CA1CA2CA9CA4CA7 | |
| SCHEMBL6532001 | 0.80 | F10 (0.43) | MEN1KMT2AHSD17B10ALDH1A1CA1 | |
| SCHEMBL6527596 | 0.79 | NOTUM (0.42) | CA1CA2CA9CA4CA7 | |
| SCHEMBL6531150 | 0.79 | NOTUM (0.42) | KMT2AALDH1A1CA1CA2CA9 | |
| SCHEMBL6529976 | 0.78 | NOTUM (0.41) | CA1CA2CA9CA4CA7 | |
| SCHEMBL6510881 | 0.78 | CA1 (0.43) | ALDH1A1CA1CA2CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | disclosed |