Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | MIF | P14174 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 4/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528013 | 0.89 | NOTUM (0.46) | NOTUMMIFCA1CA2CA9 | |
| SCHEMBL6532944 | 0.88 | ENPP2 (0.38) | NOTUMMIFRXRAGRIN1GRIN2B | |
| SCHEMBL6532001 | 0.88 | F10 (0.43) | NOTUMKDM4EMIFALDH1A1SMN1; SMN2 | |
| SCHEMBL6531150 | 0.87 | NOTUM (0.42) | NOTUMKDM4EMIFALDH1A1SMN1; SMN2 | |
| SCHEMBL6527596 | 0.87 | NOTUM (0.42) | NOTUMMIFRXRAGRIN1GRIN2B | |
| SCHEMBL6529976 | 0.86 | NOTUM (0.41) | NOTUMMIFRXRAGRIN1GRIN2B | |
| SCHEMBL6529489 | 0.85 | NOTUM (0.47) | NOTUMMIFALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6527037 | 0.85 | NOTUM (0.41) | NOTUMMIFALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL6508470 | 0.84 | MEN1 (0.40) | ALDH1A1CA1CA2CA9CA4 | |
| SCHEMBL6527383 | 0.84 | NOTUM (0.40) | NOTUMKDM4EMIFALDH1A1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | disclosed |