Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899699 | 0.92 | CA12 (0.53) | LMNAPOLBMEN1KMT2AGAA | |
| SCHEMBL8410519 | 0.88 | MRGPRX4 (0.58) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL1398536 | 0.87 | MEN1 (0.59) | LMNAPOLBMEN1KMT2AGAA | |
| SCHEMBL1748566 | 0.87 | HSD17B2 (0.56) | LMNACA12CA1CA2CA7 | |
| SCHEMBL28620700 | 0.87 | CA12 (0.48) | LMNAPOLBMEN1KMT2AGAA | |
| SCHEMBL10368252 | 0.86 | THRA (0.47) | LMNAPOLBMEN1KMT2AGAA | |
| SCHEMBL7635736 | 0.86 | KDM4E (0.50) | LMNAPOLBMEN1KMT2AGAA | |
| SCHEMBL1011945 | 0.85 | HSD17B2 (0.61) | LMNAPOLBKMT2ATDP1CA12 | |
| SCHEMBL11740137 | 0.84 | MRGPRX4 (0.57) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| Methylamine SCHEMBL5152509 | 0.84 | POLB (0.56) | LMNAPOLBMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082866-A2 | SUBSTITUTED 1, 2, 4- TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS | PFIZER LIMITED (GB) | 2005-09-09 | — | — | WO | disclosed |
| WO-2005082866-A2 | SUBSTITUTED 1, 2, 4- TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS | PFIZER LIMITED (GB) | 2005-09-09 | — | — | WO | disclosed |