Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.47 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PPP5C | P53041 | 1/20 | 0.47 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532444 | 0.71 | ALDH1A1 (0.54) | PPM1BSMN1; SMN2KDM4EGMNNLMNA | |
| SCHEMBL17532446 | 0.70 | SMN1; SMN2 (0.46) | PPM1BSMN1; SMN2KDM4EGMNNLMNA | |
| SCHEMBL19370837 | 0.68 | CRBN (0.51) | TDP1 | |
| SCHEMBL25591160 | 0.67 | — | — | |
| Demethyl-Cantharidin SCHEMBL9675442 | 0.66 | TP53 (1.00) | PPM1BSMN1; SMN2KDM4EGMNNLMNA | |
| Demethyl-Cantharidin SCHEMBL177729 | 0.66 | TP53 (1.00) | PPM1BSMN1; SMN2KDM4EGMNNLMNA | |
| Demethyl-Cantharidin SCHEMBL9906842 | 0.66 | TP53 (1.00) | PPM1BSMN1; SMN2KDM4EGMNNLMNA | |
| Norcantharidin SCHEMBL29380910 | 0.66 | TP53 (1.00) | PPM1BSMN1; SMN2KDM4EGMNNLMNA | |
| Demethyl-Cantharidin SCHEMBL3195020 | 0.66 | TP53 (1.00) | PPM1BSMN1; SMN2KDM4EGMNNLMNA | |
| Demethyl-Cantharidin SCHEMBL19318920 | 0.66 | TP53 (1.00) | PPM1BSMN1; SMN2KDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037839-A1 | NORCANTHARIDIN DERIVATIVE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | ENTOMED (FR) | 2005-04-28 | — | — | WO | disclosed |