Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CDC25A | P30304 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NPR3 | P17342 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13020623 | 0.79 | ITGA4 (0.61) | ITGA4ITGB7MAPTMEN1KMT2A | |
| SCHEMBL10584328 | 0.79 | ITGA4 (0.61) | ITGA4ITGB7MAPTMEN1KMT2A | |
| SCHEMBL10584324 | 0.79 | ITGA4 (0.61) | ITGA4ITGB7MAPTMEN1KMT2A | |
| SCHEMBL6800679 | 0.76 | ITGA4 (0.61) | ITGA4ITGB7MAPTALDH1A1CYP3A4 | |
| SCHEMBL6800676 | 0.76 | ITGA4 (0.61) | ITGA4ITGB7MAPTALDH1A1CYP3A4 | |
| SCHEMBL19945248 | 0.76 | ITGA4 (0.61) | ITGA4ITGB7MAPTALDH1A1CYP3A4 | |
| SCHEMBL19945249 | 0.76 | ITGA4 (0.61) | ITGA4ITGB7MAPTALDH1A1CYP3A4 | |
| SCHEMBL9327945 | 0.75 | MAPT (0.64) | PSMB5MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6315910 | 0.74 | CYP3A4 (0.54) | ITGA4ITGB7MAPTMEN1KMT2A | |
| SCHEMBL23901563 | 0.74 | ITGA4 (0.58) | ITGA4ITGB7MAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032794-A1 | Diamine derivatives of quinone and uses thereof | CLINICAL DATA, INC. | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032794-A1 | Diamine derivatives of quinone and uses thereof | NQO1, DPYD, NQO2 | PSMB5 2819/4885ITGA4 3857/4885ITGB7 3274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.