SCHEMBL6509079

SCHEMBL6509079

CC(=O)N[C@@H](Cc1ccc(NC(=O)c2c(Cl)cncc2Cl)cc1)C(=O)O

nearest known ligand 0.84

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 20/20 0.84
ITGA4 P13612 20/20 0.84
ITGA2 P17301 1/20 0.61
ITGB7 P26010 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6515360 0.89 ITGB1 (0.67) ITGB1ITGA4
Hydrochloric Acid SCHEMBL5365851 0.87 ITGB1 (0.78) ITGB1ITGA4
SCHEMBL6508750 0.86 ITGB1 (0.76) ITGB1ITGA4ITGA2ITGB7
SCHEMBL6530110 0.85 ITGB1 (0.83) ITGB1ITGA4ITGA2ITGB7
Hydrochloric Acid SCHEMBL5149608 0.85 ITGB1 (0.75) ITGB1ITGA4
SCHEMBL2880989 0.85 ITGB1 (0.74) ITGB1ITGA4
SCHEMBL5368033 0.84 ITGB1 (0.73) ITGB1ITGA4
SCHEMBL29646297 0.84 ITGB1 (0.88) ITGB1ITGA4ITGA2ITGB7
SCHEMBL6508908 0.84 ITGA4 (0.80) ITGB1ITGA4
Chloromethane SCHEMBL5263090 0.83 ITGB1 (0.69) ITGB1ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6911451-B1 Phenylalanine derivatives CELLTECH R&D LIMITED (GB) 2005-06-28 US disclosed