Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL3806798 | 1.00 | PRKCI (0.55) | PRKCIKDM4EMAPTRAD52TSHR | |
| Benzimidazole SCHEMBL6583805 | 0.94 | PRKCI (0.62) | PRKCIKDM4EMAPTRAD52ALDH1A1 | |
| Benzimidazole SCHEMBL1347288 | 0.89 | KDM4E (0.50) | PRKCIKDM4EMAPTRAD52ALDH1A1 | |
| Benzidine SCHEMBL29091448 | 0.89 | PRKCI (0.56) | PRKCIKDM4EMAPTRAD52ALDH1A1 | |
| Benzimidazole SCHEMBL5404384 | 0.87 | PRKCI (0.52) | PRKCIKDM4EMAPTRAD52ALDH1A1 | |
| Benzimidazole SCHEMBL29408372 | 0.87 | — | — | |
| Benzimidazole SCHEMBL29358377 | 0.87 | — | — | |
| Benzimidazole SCHEMBL461969 | 0.87 | SMN1; SMN2 (0.50) | PRKCIKDM4EMAPTRAD52ALDH1A1 | |
| Benzimidazole SCHEMBL10931770 | 0.87 | SMN1; SMN2 (0.50) | PRKCIKDM4EMAPTRAD52ALDH1A1 | |
| Benzimidazole SCHEMBL6009 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946356-A | Preparation method of benzimidazole/silica-based organic-inorganic hybrid dynamic polyimide material | 江苏海洋大学 | 2024-04-30 | — | — | CN | claimed |
| CN-109851785-A | A kind of low moisture absorption, high heat resistance type polyimides toughening polymer and preparation method thereof | 苏州予信天材新材料应用技术有限公司 | 2019-06-07 | — | — | CN | claimed |
| CN-102060779-B | Method for preparing 2-aminobenzimidazole derivative | UNIV TSINGHUA | 2012-07-25 | — | — | CN | claimed |
| CN-102060779-A | Method for preparing 2-aminobenzimidazole derivative | UNIV TSINGHUA | 2011-05-18 | — | — | CN | claimed |
| CN-1989109-A | 2-aminobenzimidazole derivatives and their use as modulators of low-conductance calcium-activated potassium channels | NEUROSEARCH AS (DK) | 2007-06-27 | — | — | CN | claimed |
| CN-1037336-A | Novel 4-chloro-3-sulphonamide benzoyl hydrazine-preparation method contains the drug component and the medical use thereof of this compound | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1989-11-22 | — | — | CN | claimed |
| CN-117946356-A | Preparation method of benzimidazole/silica-based organic-inorganic hybrid dynamic polyimide material | 江苏海洋大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-103570684-A | Phenylamine benzimidazole derivative and application of phenylamine benzimidazole derivative in preparation of anticoagulation medicine | METABOMICS INC | 2014-02-12 | — | — | CN | disclosed |
| CN-103570684-A | Phenylamine benzimidazole derivative and application of phenylamine benzimidazole derivative in preparation of anticoagulation medicine | METABOMICS INC | 2014-02-12 | — | — | CN | disclosed |
| CN-102633674-A | 2, 4, 4'-trinitrobenzene formanilide preparation method | JIANGSU SUNLIGHT PHARMACEUTICAL CHEMICAL MATERIAL CO LTD | 2012-08-15 | — | — | CN | disclosed |
| CN-102060779-B | Method for preparing 2-aminobenzimidazole derivative | UNIV TSINGHUA | 2012-07-25 | — | — | CN | disclosed |
| CN-102548970-A | Novel (6-oxo-1, 6-dihydropyrimidin-2-yl) amide derivatives, process for their preparation and their medical use as akt (pkb) phosphorylation inhibitors | SANOFI AVENTIS | 2012-07-04 | — | — | CN | disclosed |
| CN-101142208-B | 1,3-dihydro-benzimidazol-2-ylidene amines as inhibitors of respiratory syncytial virus replication | TIBOTEC PHARM LTD | 2012-05-23 | — | — | CN | disclosed |
| CN-1186326-C | Propane-1, 3-dione derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 2005-01-26 | — | — | CN | disclosed |
| CN-1558761-A | substituted benzimidazole compounds and their use in the treatment of cancer | �㶫��������ҽҩ�ɷ�����˾ | 2004-12-29 | — | — | CN | disclosed |
| CN-1440391-A | Propane-1, 3-dione derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 2003-09-03 | — | — | CN | disclosed |
| CN-1410047-A | Composition containing specific single cation monoazo dye for dyeing human cutin fiber | OREAL (FR) | 2003-04-16 | — | — | CN | disclosed |
| CN-1395568-A | 1,2-diaryl benzimidazole derivative for treating illnesses associated with microglia activation | SCHERING AG (DE) | 2003-02-05 | — | — | CN | disclosed |
| CN-1333768-A | Pyrimidinylbenzimidazole and triazinylbenzimidazole derivatives and agricultural/horticultural bactericides | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2002-01-30 | — | — | CN | disclosed |
| CN-1037336-A | Novel 4-chloro-3-sulphonamide benzoyl hydrazine-preparation method contains the drug component and the medical use thereof of this compound | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1989-11-22 | — | — | CN | disclosed |