Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 4/20 | 0.82 |
| ▸ | POLB | P06746 | 1/20 | 0.81 |
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.69 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.69 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17946047 | 0.92 | POLB (0.91) | CCR8POLBADIPOR2ADIPOR1MCHR1 | |
| SCHEMBL6499380 | 0.90 | CCR8 (1.00) | CCR8SIGMAR1 | |
| SCHEMBL6500103 | 0.88 | CCR8 (1.00) | CCR8POLBSIGMAR1 | |
| SCHEMBL6498271 | 0.87 | CCR8 (0.82) | CCR8POLBSIGMAR1 | |
| SCHEMBL5129236 | 0.86 | MCHR1 (0.83) | POLBADIPOR2ADIPOR1MCHR1USP2 | |
| SCHEMBL6507394 | 0.84 | CCR8 (0.78) | CCR8MCHR1SIGMAR1PRKAA2 | |
| SCHEMBL6504896 | 0.84 | CCR8 (0.88) | CCR8SIGMAR1 | |
| SCHEMBL6500525 | 0.84 | CCR8 (0.88) | CCR8SIGMAR1 | |
| SCHEMBL6499300 | 0.83 | CCR8 (0.75) | CCR8POLBADIPOR2ADIPOR1MCHR1 | |
| SCHEMBL6499292 | 0.83 | CCR8 (0.75) | CCR8POLBADIPOR2ADIPOR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | CCR8 1/4885POLB 3458/4885ADIPOR2 1334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.