Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510578 | 0.90 | POLB (0.45) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6510830 | 0.85 | POLB (0.45) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6510768 | 0.84 | ALDH1A1 (0.43) | POLBHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6533581 | 0.84 | POLB (0.38) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6511861 | 0.82 | CA12 (0.45) | POLBHDAC1HDAC6MAPK1ALDH1A1 | |
| SCHEMBL6508460 | 0.81 | HTR2C (0.36) | HDAC3HDAC1HDAC2HDAC8MAPT | |
| SCHEMBL6515092 | 0.80 | POLB (0.48) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6510328 | 0.80 | HTR2C (0.37) | HDAC3HDAC1HDAC2HDAC8MAPT | |
| SCHEMBL6511885 | 0.80 | POLB (0.47) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6518329 | 0.79 | NPC1 (0.39) | HDAC3HDAC1HDAC2HDAC8MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |