Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511823 | 0.86 | LTB4R (0.40) | MEP1BHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6510768 | 0.86 | ALDH1A1 (0.43) | HTR2CHTR6MEP1BHDAC3HDAC1 | |
| SCHEMBL6508460 | 0.85 | HTR2C (0.36) | HTR2CHTR6MEP1BSIRT2HDAC3 | |
| SCHEMBL6511994 | 0.83 | TSHR (0.50) | FFAR1 | |
| SCHEMBL6518329 | 0.81 | NPC1 (0.39) | HTR2CHTR6MEP1BHDAC3HDAC1 | |
| SCHEMBL6509298 | 0.80 | POLB (0.42) | HDAC3HDAC1HDAC2HDAC8MAPT | |
| SCHEMBL6510304 | 0.80 | EGFR (0.42) | HTR2CHTR6MEP1BMEN1MAPT | |
| SCHEMBL6509305 | 0.80 | ALDH1A1 (0.38) | MEP1BLMNAMEN1MAPTKMT2A | |
| SCHEMBL6510314 | 0.79 | HPGD (0.40) | HTR2CHTR6MEP1BMAPTHPGD | |
| SCHEMBL6509442 | 0.79 | RAB9A (0.41) | HTR2CHTR6MEP1BHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |