Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491284 | 0.78 | RXRA (0.35) | RXRARXRBRXRG | |
| SCHEMBL20563902 | 0.73 | NOS3 (0.32) | — | |
| SCHEMBL744891 | 0.73 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL5735496 | 0.71 | KDM1A (0.51) | KDM1A | |
| SCHEMBL26607136 | 0.69 | RXRA (0.46) | RXRARXRBRXRGKDM1A | |
| SCHEMBL6086554 | 0.69 | RXRA (0.46) | RXRARXRBRXRGKDM1A | |
| SCHEMBL30573101 | 0.69 | RXRA (0.46) | RXRARXRBRXRGKDM1A | |
| SCHEMBL10515346 | 0.68 | RXRA (0.39) | RXRARXRBRXRGKDM1A | |
| SCHEMBL6085848 | 0.68 | HTR2A (0.46) | RXRARXRBRXRG | |
| SCHEMBL8308844 | 0.67 | RXRA (0.43) | RXRARXRBRXRGKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042509-A1 | 7-`(7-ALKOXY)-CHROM-3-EN-6-YL!-HEPTATRIENOIC ACID AND 7-`(3ALKOXY)-5,6-DIHYDRONAPHTHALEN-2-YL!-HEPTATRIENOIC ACID DERIVATIVES MODULATORS | ALLERGAN, INC. (US) | 2005-05-12 | — | — | WO | disclosed |