⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646994 | 0.78 | — | — | |
| SCHEMBL27740885 | 0.73 | — | — | |
| SCHEMBL24126 | 0.69 | — | — | |
| SCHEMBL20315181 | 0.67 | GABRP (0.31) | — | |
| Methacrylic Acid SCHEMBL8824602 | 0.67 | TET2 (0.37) | — | |
| Charcoal, Activated SCHEMBL30472884 | 0.67 | HSD17B10 (0.39) | — | |
| Methyl Alcohol SCHEMBL28502957 | 0.67 | — | — | |
| SCHEMBL28342941 | 0.67 | — | — | |
| Alcohol SCHEMBL11362553 | 0.65 | — | — | |
| SCHEMBL5355933 | 0.65 | CAMK2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118187-B1 | POLYLACTIDE-BASED COMPOSITIONS | MATERIA NOVA (BE) | 2012-09-26 | — | — | EP | claimed |
| US-8119713-B2 | Polylactide-based compositions | MATERIA NOVA (BE) | 2012-02-21 | — | — | US | claimed |
| EP-2118187-A1 | POLYLACTIDE-BASED COMPOSITIONS | Materia Nova (BE) | 2009-11-18 | — | — | EP | claimed |
| WO-2008095874-A1 | POLYLACTIDE-BASED COMPOSITIONS | MATERIA NOVA (BE) | 2008-08-14 | — | — | WO | claimed |
| EP-2118187-B1 | POLYLACTIDE-BASED COMPOSITIONS | MATERIA NOVA (BE) | 2012-09-26 | — | — | EP | disclosed |
| EP-2118187-A1 | POLYLACTIDE-BASED COMPOSITIONS | Materia Nova (BE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008095874-A1 | POLYLACTIDE-BASED COMPOSITIONS | MATERIA NOVA (BE) | 2008-08-14 | — | — | WO | disclosed |
| US-20050176773-A1 | Antiproliferative 2-(heteroaryl)-aminothiazole compounds and pharmaceutical compositions, and method for their use | AGOURON PHARMACEUTICALS, INC. | 2005-08-11 | — | — | US | disclosed |
| US-20050038078-A1 | Antiproliferative 2-(heteroaryl)-aminothiazole compounds and pharmaceutical compositions, and methods for their use | AGOURON PHARMACEUTICALS, INC. | 2005-02-17 | — | — | US | disclosed |
| WO-2004014904-A1 | ANTIPROLIFERATIVE 2-(HETEROARYL)-AMINOTHIAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE | PFIZER INC. (US) | 2004-02-19 | — | — | WO | disclosed |