Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19558131 | 0.89 | LMNA (0.33) | ALDH1A1 | |
| SCHEMBL18649822 | 0.89 | LMNA (0.33) | ALDH1A1 | |
| SCHEMBL18551463 | 0.89 | LMNA (0.33) | ALDH1A1 | |
| SCHEMBL20824834 | 0.87 | OPRM1 (0.32) | — | |
| SCHEMBL20915188 | 0.82 | NR1I2 (0.36) | — | |
| SCHEMBL20936526 | 0.82 | NR1I2 (0.36) | — | |
| SCHEMBL20915223 | 0.82 | NR1I2 (0.36) | — | |
| SCHEMBL20915422 | 0.82 | NR1I2 (0.36) | — | |
| SCHEMBL20915291 | 0.82 | NR1I2 (0.36) | — | |
| SCHEMBL20936419 | 0.82 | NR1I2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005068418-A1 | SULFIDE AND DISULFIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | WO | disclosed |