Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.53 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509296 | 0.88 | PTGDR2 (0.41) | PTGDR2AKR1B1LIPEMCL1HTR1A | |
| SCHEMBL3006325 | 0.80 | PTGDR2 (0.52) | PTGDR2AKR1B1LIPEMCL1HTR1A | |
| SCHEMBL1385122 | 0.71 | PTGDR2 (0.87) | PTGDR2AKR1B1 | |
| SCHEMBL1385757 | 0.71 | PTGDR2 (0.75) | PTGDR2AKR1B1MCL1 | |
| SCHEMBL1386058 | 0.70 | PTGDR2 (0.73) | PTGDR2AKR1B1 | |
| SCHEMBL1386979 | 0.70 | PTGDR2 (1.00) | PTGDR2AKR1B1 | |
| SCHEMBL1386057 | 0.70 | PTGDR2 (0.62) | PTGDR2AKR1B1MCL1HTR6 | |
| SCHEMBL3005489 | 0.69 | PTGDR2 (0.48) | PTGDR2AKR1B1LIPEMCL1HTR1A | |
| SCHEMBL6512250 | 0.69 | PTGDR2 (0.63) | PTGDR2AKR1B1 | |
| SCHEMBL3010803 | 0.69 | PTGDR2 (0.70) | PTGDR2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121141-A1 | PYRROLOPYRIDINE DERIVATIVES AND USE THEREOF FOR TREATING DISEASES MEDIATED BY PROSTAGLANDIN D2 (PGD2) | OXAGEN LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |