Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509623 | 0.88 | PTGDR2 (0.53) | PTGDR2AKR1B1LIPEHTR1AHTR2A | |
| SCHEMBL3557583 | 0.73 | PTGDR2 (0.59) | PTGDR2AKR1B1POLBNPSR1CA12 | |
| SCHEMBL3556759 | 0.72 | PTGDR2 (0.77) | PTGDR2AKR1B1CA12CA1CA2 | |
| SCHEMBL6512107 | 0.71 | PTGDR2 (0.50) | PTGDR2AKR1B1POLBNPSR1HTR1A | |
| SCHEMBL6509625 | 0.71 | PTGDR2 (0.53) | PTGDR2AKR1B1NPSR1HTR1AHTR2A | |
| SCHEMBL10458998 | 0.64 | NPSR1 (0.49) | POLBNPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1464359 | 0.62 | KMT2A (0.73) | POLBNPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL2332913 | 0.61 | ADRB2 (0.65) | POLBADRB2CA12CA1CA2 | |
| SCHEMBL7870795 | 0.60 | ALDH1A1 (0.71) | POLBALDH1A1MEN1KMT2AGAA | |
| SCHEMBL12102109 | 0.60 | KMT2A (0.53) | POLBADRB2NPSR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121141-A1 | PYRROLOPYRIDINE DERIVATIVES AND USE THEREOF FOR TREATING DISEASES MEDIATED BY PROSTAGLANDIN D2 (PGD2) | OXAGEN LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |