Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512064 | 0.91 | PTGDR2 (0.60) | PTGDR2AKR1B1 | |
| SCHEMBL6512958 | 0.88 | PTGDR2 (0.55) | PTGDR2AKR1B1 | |
| SCHEMBL6512107 | 0.87 | PTGDR2 (0.50) | PTGDR2AKR1B1 | |
| SCHEMBL1386058 | 0.81 | PTGDR2 (0.73) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL6509282 | 0.81 | PTGDR2 (0.69) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL3010803 | 0.80 | PTGDR2 (0.70) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL3001517 | 0.78 | PTGDR2 (0.68) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL13208600 | 0.78 | PTGDR2 (0.68) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1385122 | 0.78 | PTGDR2 (0.87) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1385757 | 0.78 | PTGDR2 (0.75) | PTGDR2AKR1B1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121141-A1 | PYRROLOPYRIDINE DERIVATIVES AND USE THEREOF FOR TREATING DISEASES MEDIATED BY PROSTAGLANDIN D2 (PGD2) | OXAGEN LIMITED (GB) | 2005-12-22 | — | — | WO | claimed |
| WO-2005121141-A1 | PYRROLOPYRIDINE DERIVATIVES AND USE THEREOF FOR TREATING DISEASES MEDIATED BY PROSTAGLANDIN D2 (PGD2) | OXAGEN LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |