Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 13/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 11/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036797 | 0.89 | CDK1 (0.34) | XDH | |
| SCHEMBL516302 | 0.78 | ADORA2A (0.39) | LMNA | |
| Trifluoroacetic Acid SCHEMBL3132981 | 0.77 | HRH4 (0.38) | HRH4HRH3XDH | |
| SCHEMBL67129 | 0.75 | CDK1 (0.31) | — | |
| Trifluoroacetic Acid SCHEMBL21048086 | 0.74 | KDM4E (0.37) | HRH4HRH3 | |
| SCHEMBL48130 | 0.70 | CYP1A2 (0.35) | — | |
| SCHEMBL8219211 | 0.70 | NOS1 (0.38) | XDHLMNA | |
| SCHEMBL8215833 | 0.70 | NOS1 (0.38) | XDHLMNA | |
| SCHEMBL2306213 | 0.69 | CDK1 (0.32) | — | |
| Adenine SCHEMBL28086748 | 0.68 | MTAP (0.39) | HRH4HRH3DRD3XDHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050153357-A1 | Bioactive sensors | EICHLER JUTTA (DE) | 2005-07-14 | — | — | US | disclosed |
| US-20020127577-A1 | Bioactive sensors | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-09-12 | — | — | US | disclosed |