Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | PI4KA | P42356 | 2/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29808400 | 0.88 | PDPK1 (0.51) | HRH4HRH3PDPK1GDAPIN1 | |
| SCHEMBL1374742 | 0.88 | PDPK1 (0.51) | HRH4HRH3PDPK1GDAPIN1 | |
| SCHEMBL38912 | 0.88 | PDPK1 (0.51) | HRH4HRH3PDPK1GDAPIN1 | |
| SCHEMBL29605437 | 0.82 | PDPK1 (0.54) | PDPK1GDAKDRAURKBPIN1 | |
| SCHEMBL67130 | 0.82 | PDPK1 (0.54) | PDPK1GDAKDRAURKBPIN1 | |
| SCHEMBL10361596 | 0.82 | PDPK1 (0.45) | PDPK1GDAKDRAURKBPI4KA | |
| SCHEMBL725881 | 0.79 | PDPK1 (0.50) | PDPK1GDAKDRAURKBPIN1 | |
| SCHEMBL28873092 | 0.77 | GDA (0.49) | PDPK1GDAKDRAURKBPIN1 | |
| SCHEMBL6379588 | 0.77 | PDPK1 (0.58) | PDPK1GDAKDRAURKBPIN1 | |
| SCHEMBL30610405 | 0.76 | CDK1 (0.53) | PDPK1GDAPIN1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050153357-A1 | Bioactive sensors | EICHLER JUTTA (DE) | 2005-07-14 | — | — | US | disclosed |
| US-20020127577-A1 | Bioactive sensors | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-09-12 | — | — | US | disclosed |