Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.58 |
| ▸ | DRD3 | P35462 | 3/20 | 0.58 |
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10372869 | 0.99 | LMNA (0.57) | DRD2DRD3HTR6HTR3EHTR3B | |
| SCHEMBL10914809 | 0.87 | DRD4 (0.60) | DRD2DRD3MAPTALDH1A1MAPK1 | |
| SCHEMBL13648743 | 0.85 | POLB (0.65) | DRD2DRD3HTR6HTR3EHTR3B | |
| SCHEMBL7966605 | 0.83 | DRD2 (0.63) | DRD2DRD3HTR6HTR3EHTR3B | |
| SCHEMBL6506614 | 0.82 | DRD2 (0.58) | DRD2DRD3HTR6HTR3EHTR3B | |
| SCHEMBL8828444 | 0.82 | DRD2 (0.58) | DRD2DRD3HTR6HTR3EHTR3B | |
| SCHEMBL10746398 | 0.82 | DRD2 (0.58) | DRD2DRD3HTR6HTR3EHTR3B | |
| SCHEMBL8957751 | 0.82 | DRD2 (0.58) | DRD2DRD3HTR6HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL11869458 | 0.82 | DRD2 (0.61) | DRD2DRD3HTR6HTR3EHTR3B | |
| SCHEMBL278126 | 0.80 | DRD2 (0.67) | DRD2DRD3HTR6HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021522-A1 | SYNTHESIS OF 1-‘4-(2-METHOXYPHENYL) PIPERAZIN-1-YL !-3-(2,6-DIOXOPIPERIDIN-1-YL) PROPANE | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-10 | — | — | WO | disclosed |
| EP-1097134-A1 | ARYLPIPERAZINE DERIVATIVES USEFUL AS UROSELECTIVE ALPHA1-ADRENOCEPTOR BLOCKERS | RANBAXY LABORATORIES, LTD. (IN) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000005206-A1 | ARYLPIPERAZINE DERIVATIVES USEFUL AS URO-SELECTIVE ALPHA-1-ADRENOCEPTOR BLOCKERS | RANBAXY LABORATORIES LIMITED (US) | 2000-02-03 | — | — | WO | disclosed |
| WO-2000005205-A1 | ARYLPIPERAZINE DERIVATIVES USEFUL AS UROSELECTIVE ALPHA1-ADRENOCEPTOR BLOCKERS | RANBAXY LABORATORIES LIMITED (US) | 2000-02-03 | — | — | WO | disclosed |