Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 17/20 | 0.94 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509265 | 0.86 | DHODH (0.72) | DHODHPDE10ATSHR | |
| SCHEMBL20659638 | 0.83 | DHODH (0.68) | DHODHPDE10ATSHR | |
| SCHEMBL1581468 | 0.81 | PDE10A (1.00) | DHODHPDE10ATSHR | |
| SCHEMBL9954367 | 0.80 | DHODH (0.63) | DHODHPDE10ATSHR | |
| Hydrochloric Acid SCHEMBL27511204 | 0.80 | PDE10A (0.97) | DHODHPDE10ATSHR | |
| SCHEMBL2124987 | 0.79 | DHODH (0.62) | DHODHPDE10ATSHR | |
| SCHEMBL28170815 | 0.77 | DHODH (0.73) | DHODHPDE10ATSHR | |
| SCHEMBL2807617 | 0.76 | PDE10A (0.77) | DHODHPDE10ATSHR | |
| SCHEMBL18075791 | 0.75 | PDE10A (0.75) | DHODHPDE10ATSHR | |
| SCHEMBL4228780 | 0.74 | DHODH (0.70) | DHODHPDE10ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000845-A2 | BICYCLIC DERIVATIVES AS NK-1 AND NK-2 ANTAGONISTS | NIKEM RESEARCH S.R.L. (IT) | 2005-01-06 | — | — | WO | disclosed |