Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501188 | 0.83 | TDP1 (0.60) | MAPTHTTGPR174ALDH1A1MAPK1 | |
| SCHEMBL3435055 | 0.83 | MAPT (0.74) | MAPTTP53HTTGPR174ALDH1A1 | |
| SCHEMBL13648194 | 0.81 | MAPT (0.64) | MAPTTP53HTTGPR174ALDH1A1 | |
| SCHEMBL7475373 | 0.81 | MAPT (0.56) | MAPTTP53HTTGPR174ALDH1A1 | |
| SCHEMBL13999700 | 0.79 | MAPT (0.75) | MAPTTP53HTTGPR174ALDH1A1 | |
| SCHEMBL6529147 | 0.78 | MAPT (0.68) | MAPTTP53HTTALDH1A1CTSB | |
| SCHEMBL38658829 | 0.78 | MAPT (0.75) | MAPTTP53HTTGPR174ALDH1A1 | |
| SCHEMBL3435998 | 0.78 | MAPT (0.74) | MAPTTP53HTTALDH1A1CTSB | |
| SCHEMBL12643869 | 0.78 | MAPT (0.70) | MAPTTP53HTTALDH1A1CTSB | |
| SCHEMBL3435047 | 0.78 | MAPT (0.69) | MAPTTP53HTTALDH1A1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019200-A2 | ARYL PIPERIDINE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |