SCHEMBL6509840

SCHEMBL6509840

CON=c1sc2cc(N3C[C@@H](CN)OC3=O)ccc2n1C

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.44
GRM2 Q14416 7/20 0.37
MAOB P27338 4/20 0.36
MAOA P21397 3/20 0.36
LMNA P02545 1/20 0.35
PTGS1 P23219 1/20 0.35
CALML3 P27482 1/20 0.35
SDHA P31040 1/20 0.35
KDM4E B2RXH2 1/20 0.34
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6509842 1.00 F10 (0.44) F10GRM2MAOBMAOALMNA
SCHEMBL6509746 0.90 F10 (0.43) F10GRM2MAOBMAOAKDM4E
SCHEMBL6509751 0.90 F10 (0.43) F10GRM2MAOBMAOAKDM4E
SCHEMBL6508377 0.89 F10 (0.41) F10GRM2MAOBMAOACALML3
SCHEMBL6508380 0.89 F10 (0.41) F10GRM2MAOBMAOACALML3
SCHEMBL6512664 0.85 MAOA (0.54) F10MAOBMAOALMNAPTGS1
SCHEMBL6512668 0.85 MAOA (0.54) F10MAOBMAOALMNAPTGS1
SCHEMBL6511733 0.85 MAOB (0.39) F10GRM2MAOBMAOALMNA
SCHEMBL79733 0.84 F10 (0.50) F10GRM2MAOBMAOA
SCHEMBL6513194 0.84 F10 (0.44) F10MAOBMAOALMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005082900-A2 OXAZOLIDINONE AMIDOXIMES AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2005-09-09 WO disclosed