Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | F10 | P00742 | 6/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CALML3 | P27482 | 1/20 | 0.38 |
| ▸ | SDHA | P31040 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516105 | 0.91 | MAOB (0.42) | MAOBF10MAOALMNAPTGS1 | |
| SCHEMBL6509769 | 0.90 | MAOB (0.41) | MAOBF10MAOALMNAPTGS1 | |
| SCHEMBL6512664 | 0.86 | MAOA (0.54) | MAOBF10MAOALMNAPTGS1 | |
| SCHEMBL6512668 | 0.86 | MAOA (0.54) | MAOBF10MAOALMNAPTGS1 | |
| SCHEMBL6509842 | 0.85 | F10 (0.44) | MAOBF10MAOALMNAPTGS1 | |
| SCHEMBL6509840 | 0.85 | F10 (0.44) | MAOBF10MAOALMNAPTGS1 | |
| SCHEMBL6511736 | 0.83 | MAOA (0.51) | MAOBF10MAOALMNAPTGS1 | |
| SCHEMBL6513194 | 0.82 | F10 (0.44) | MAOBF10MAOALMNAPTGS1 | |
| SCHEMBL6513198 | 0.82 | F10 (0.44) | MAOBF10MAOALMNAPTGS1 | |
| SCHEMBL6515849 | 0.82 | MAOB (0.42) | MAOBF10MAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082900-A2 | OXAZOLIDINONE AMIDOXIMES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |