SCHEMBL6509882

SCHEMBL6509882

CO[Si](CC(N)CC(C)N)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4436655 0.82
SCHEMBL135373 0.79 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1
SCHEMBL28719546 0.79 OPRM1 (0.31)
SCHEMBL28359214 0.77 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1
SCHEMBL28653228 0.77 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1
Ammonia Solution, Strong SCHEMBL9559498 0.77 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1
SCHEMBL30856515 0.76 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1
SCHEMBL4654321 0.75
SCHEMBL231366 0.75 ALDH1A1 (0.32) ALDH1A1
SCHEMBL9861317 0.72 CYP2D6 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050243268-A1 Pair of substrates spaced from each other by spacers having a pre-determined pattern and method of making thereof KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2005-11-03 US disclosed
EP-1543380-A1 A PAIR OF SUBSTRATES SPACED FROM EACH OTHER BY SPACERS HAVING A PRE-DETERMINED PATTERN AND METHOD OF MAKING THEREOF Koninklijke Philips Electronics N.V. (NL) 2005-06-22 EP disclosed
WO-2004027501-A1 A PAIR OF SUBSTRATES SPACED FROM EACH OTHER BY SPACERS HAVING A PRE-DETERMINED PATTERN AND METHOD OF MAKING THEREOF KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-04-01 WO disclosed