Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | ESRRB | O95718 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2430956 | 0.87 | ALDH1A1 (0.60) | KMT2AESRRBL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL17992038 | 0.84 | ALDH1A1 (0.57) | KMT2AESRRBL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL29041154 | 0.84 | KMT2A (1.00) | KMT2AESRRBL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL28658680 | 0.84 | KMT2A (0.74) | KMT2AESRRBL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL26817889 | 0.83 | KMT2A (0.59) | KMT2AESRRBL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL13076771 | 0.83 | ESRRB (0.57) | KMT2AESRRBL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL11262738 | 0.83 | KMT2A (0.50) | KMT2AESRRBL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL135355 | 0.81 | L3MBTL1 (0.66) | KMT2AL3MBTL1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9751251 | 0.81 | KMT2A (0.70) | KMT2AESRRBL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL4561514 | 0.81 | ALDH1A1 (0.61) | KMT2AESRRBSMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590056-B2 | ERR modulators and uses thereof | CITY OF HOPE (US) | 2020-03-17 | — | — | US | disclosed |
| US-20180297923-A1 | ERR MODULATORS AND USES THEREOF | CITY OF HOPE | 2018-10-18 | — | — | US | disclosed |
| WO-2005051380-A1 | SUBSTITUTED UREA-OCTAHYDROINDOLS AS ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR 1 (MCH1R) | BIOVITRUM AB (SE) | 2005-06-09 | — | — | WO | disclosed |
| WO-2005035497-A1 | CASPASE INHIBITOR COMPRISING 2-ALKYL-4-OXOBUTANOYL GROUP AND PHARMACEUTICAL COMPOSITION THEREOF | LG LIFE SCIENCES LTD. (KR) | 2005-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180297923-A1 | ERR MODULATORS AND USES THEREOF | ESRRA, ESRRB, ESRRG | KMT2A 1958/4885ESRRB 2/4885L3MBTL1 3369/4885 |
| US-10590056-B2 | ERR modulators and uses thereof | ESRRA, ESRRB, ESRRG | KMT2A 1958/4885ESRRB 2/4885L3MBTL1 3369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.