Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6510018

NC(=S)NCC1CC1.O=C(O)C(F)(F)F

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.52
CYP2D6 P10635 1/20 0.39
HDAC6 Q9UBN7 5/20 0.38
HDAC4 P56524 3/20 0.38
HDAC3 O15379 2/20 0.38
HDAC1 Q13547 1/20 0.38
MLYCD O95822 1/20 0.38
CYP2C19 P33261 1/20 0.36
F2 P00734 3/20 0.34
PRSS1 P07477 2/20 0.34
EPHX1 P07099 2/20 0.34
LIPC P11150 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
EPHX2 P34913 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1960773 0.82
Trifluoroacetic Acid SCHEMBL21813736 0.81 CYP2D6 (0.52) TDP1CYP2D6HDAC6HDAC4HDAC3
Trifluoroacetic Acid SCHEMBL5348233 0.79 TDP1 (0.42) TDP1HDAC6MLYCDDPP8DPP7
Trifluoroacetic Acid SCHEMBL1998431 0.79 TDP1 (0.47) TDP1CYP2D6HDAC6HDAC4HDAC3
SCHEMBL5127504 0.77 TDP1 (0.50) TDP1CYP2D6EPHX1ALDH1A1
SCHEMBL8391864 0.74 TDP1 (0.48) TDP1CYP2D6HDAC6HDAC4HDAC3
SCHEMBL3899220 0.74 TDP1 (0.46) TDP1CYP2D6F2PRSS1EPHX1
SCHEMBL14416204 0.73 ACACB (0.49) TDP1EPHX1
SCHEMBL9431190 0.72 TDP1 (0.52) TDP1HDAC6HDAC4HDAC3HDAC1
SCHEMBL2282942 0.72 EPHX1 (0.50) TDP1CYP2D6HDAC6HDAC4HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005051380-A1 SUBSTITUTED UREA-OCTAHYDROINDOLS AS ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR 1 (MCH1R) BIOVITRUM AB (SE) 2005-06-09 WO claimed