Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380295 | 0.87 | — | — | |
| Trifluoroacetic Acid SCHEMBL5348233 | 0.82 | TDP1 (0.42) | TDP1HDAC6MLYCDALDH1A1CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL21813736 | 0.81 | CYP2D6 (0.52) | TDP1CYP2D6HDAC6MLYCDALDH1A1 | |
| SCHEMBL8601731 | 0.80 | PLG (0.57) | TDP1CYP2D6ARG1ALDH1A1EPHX1 | |
| SCHEMBL9795157 | 0.79 | TDP1 (0.52) | TDP1CYP2D6ARG1ALDH1A1CYP3A4 | |
| SCHEMBL9795153 | 0.79 | TDP1 (0.52) | TDP1CYP2D6ARG1ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8117093 | 0.79 | PLG (0.55) | TDP1CYP2D6ARG1ALDH1A1EPHX1 | |
| Trifluoroacetic Acid SCHEMBL6510018 | 0.79 | TDP1 (0.52) | TDP1CYP2D6HDAC6MLYCDALDH1A1 | |
| SCHEMBL18235911 | 0.78 | TDP1 (0.50) | TDP1CYP2D6ARG1ALDH1A1CYP3A4 | |
| SCHEMBL10702291 | 0.77 | CYP2D6 (0.61) | TDP1CYP2D6ALDH1A1EPHX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960560-B2 | 1-(biphenyl-4-ylmethyl)imidazolidine-2,4-dione | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | disclosed |
| US-20100144723-A1 | 1-(BIPHENYL-4-YLMETHYL)IMIDAZOLIDINE-2,4-DIONE | N. V. ORGANON | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144723-A1 | 1-(BIPHENYL-4-YLMETHYL)IMIDAZOLIDINE-2,4-DIONE | OPRM1, OR10J3, OPRD1 | TDP1 2858/4885CYP2D6 452/4885ARG1 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.