Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24810210 | 0.84 | GRM5 (0.33) | HRH1IDH1 | |
| SCHEMBL3998636 | 0.67 | HRH1 (0.35) | HRH1BRD4 | |
| SCHEMBL22736587 | 0.64 | ALDH1A1 (0.33) | — | |
| SCHEMBL3997401 | 0.63 | GAA (0.35) | HRH1IDH1 | |
| SCHEMBL13937963 | 0.63 | JAK2 (0.34) | — | |
| SCHEMBL18839209 | 0.60 | BRD4 (0.33) | BRD4 | |
| SCHEMBL23768705 | 0.60 | MAP3K5 (0.36) | — | |
| SCHEMBL20939379 | 0.60 | HRH3 (0.34) | IDH1 | |
| SCHEMBL19164218 | 0.59 | ADRA1A (0.31) | — | |
| SCHEMBL11971142 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061506-A1 | BICYCLIC PYRAZOLYL AND IMIDAZOLYL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |