Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.44 |
| ▸ | CTSS | P25774 | 11/20 | 0.39 |
| ▸ | CTSL | P07711 | 9/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510161 | 0.91 | CTSK (0.44) | CTSKCTSSCTSL | |
| SCHEMBL6513831 | 0.90 | CTSK (0.44) | CTSKCTSSCTSL | |
| SCHEMBL6506223 | 0.90 | CTSK (0.42) | CTSKCTSSCTSL | |
| SCHEMBL6512174 | 0.88 | CTSK (0.40) | CTSK | |
| SCHEMBL6512111 | 0.88 | CTSK (0.38) | CTSK | |
| SCHEMBL6512117 | 0.88 | CTSK (0.38) | CTSK | |
| SCHEMBL6512168 | 0.88 | CTSK (0.40) | CTSK | |
| SCHEMBL6527852 | 0.88 | CTSK (0.40) | CTSKCTSSCTSL | |
| SCHEMBL6513016 | 0.87 | CTSK (0.43) | CTSKCTSSCTSL | |
| SCHEMBL6509302 | 0.87 | PDPK1 (0.41) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003103-A2 | 2, 4, 6-TRI-SUBSTITUTED 6-MEMBERED HETEROCYCLES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | ASTRAZENECA AB (SE) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003103-A2 | 2, 4, 6-TRI-SUBSTITUTED 6-MEMBERED HETEROCYCLES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | ASTRAZENECA AB (SE) | 2005-01-13 | — | — | WO | disclosed |