Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460086 | 0.84 | ALDH1A1 (0.43) | NOTUMSMN1; SMN2CYP1A2CYP3A4HTT | |
| SCHEMBL28383789 | 0.83 | TDP1 (0.44) | NOTUMSMN1; SMN2CYP1A2CYP3A4HTT | |
| SCHEMBL23326387 | 0.80 | MEN1 (0.43) | SMN1; SMN2HTTKMT2ANPC1RAB9A | |
| SCHEMBL28386387 | 0.79 | GAA (0.40) | NOTUMSMN1; SMN2CYP1A2CYP2C19KMT2A | |
| SCHEMBL30910832 | 0.77 | TSHR (0.52) | NOTUMSMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL12850729 | 0.75 | TSHR (0.45) | NOTUMSMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL11332939 | 0.74 | TDP1 (0.35) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL9417471 | 0.74 | SMN1; SMN2 (0.41) | NOTUMSMN1; SMN2HTTPOLBTSHR | |
| SCHEMBL3066977 | 0.72 | NOTUM (0.49) | NOTUMSMN1; SMN2HTTPOLBTSHR | |
| SCHEMBL944403 | 0.71 | LMNA (0.49) | SMN1; SMN2TSHRKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102388037-B | Quinazolinones as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV | 2014-12-03 | — | — | CN | disclosed |
| CN-102388037-A | Quinazolinones as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV | 2012-03-21 | — | — | CN | disclosed |
| WO-2005037839-A1 | NORCANTHARIDIN DERIVATIVE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | ENTOMED (FR) | 2005-04-28 | — | — | WO | disclosed |
| EP-0261837-B1 | Process for the preparation of electrically conductive material | SANYO ELECTRIC CO (JP) | 2001-07-11 | — | — | EP | disclosed |
| EP-0646837-B1 | Clad vanadium pentoxide materials, conductive layers and photographic elements containing the same | EASTMAN KODAK CO (US) | 1999-08-04 | — | — | EP | disclosed |
| US-5654089-A | IMAGING ELEMENTS | EASTMAN KODAK COMPANY (US) | 1997-08-05 | — | — | US | disclosed |
| US-5455153-A | Cladding is a oxidatively polymerizable polymer | EASTMAN KODAK COMPANY (US) | 1995-10-03 | — | — | US | disclosed |
| EP-0646837-A1 | Clad vanadium pentoxide materials, conductive layers and photographic elements containing the same | EASTMAN KODAK COMPANY (US) | 1995-04-05 | — | — | EP | disclosed |
| US-4795687-A | POLYTHIENYLENE, POLYPRYRROLE OR POLYANILINE MATERIAL PREPARED BY OXIDATION POLYMERIZATION | MITSUBISHI KASEI CORP. (JP) | 1989-01-03 | — | — | US | disclosed |