Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.58 |
| ▸ | HTR2B | P41595 | 6/20 | 0.58 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509968 | 0.88 | HTR2C (0.57) | HTR2CHTR2BGID4KDM4EHDAC3 | |
| SCHEMBL20510961 | 0.85 | HTR2C (0.68) | HTR2CHTR2BGID4HTR2AKDM4E | |
| SCHEMBL20510918 | 0.85 | HTR2C (0.68) | HTR2CHTR2BGID4HTR2AKDM4E | |
| SCHEMBL6518480 | 0.84 | HTR2C (0.68) | HTR2CHTR2BGID4HTR2AKDM4E | |
| SCHEMBL6510239 | 0.84 | HTR2C (0.77) | HTR2CHTR2BKDM4EHDAC3HDAC1 | |
| SCHEMBL6508031 | 0.84 | HTR2C (0.77) | HTR2CHTR2BKDM4EHDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL30001584 | 0.83 | HTR2C (0.76) | HTR2CHTR2BKDM4EHDAC3HDAC1 | |
| SCHEMBL6508698 | 0.81 | HTR2C (0.72) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL6507506 | 0.81 | HTR2C (0.72) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| Fumaric Acid SCHEMBL20510427 | 0.81 | HTR2C (0.62) | HTR2CHTR2BGID4LMNAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040108-A1 | PROLINAMIDE DERIVATIVES AS SODIUM AND/OR CALCIUM CHANNEL BLOCKERS OR SELECTIVE MAO-B INHIBITORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040108-A1 | PROLINAMIDE DERIVATIVES AS SODIUM AND/OR CALCIUM CHANNEL BLOCKERS OR SELECTIVE MAO-B INHIBITORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | disclosed |