Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15127785 | 0.98 | BTK (0.34) | EPHX1BTKS1PR1GAAPDE4A | |
| SCHEMBL12946742 | 0.81 | EPHX1 (0.39) | EPHX1BTKS1PR1GAAPDE4A | |
| SCHEMBL27780875 | 0.77 | BTK (0.35) | EPHX1BTK | |
| SCHEMBL7296069 | 0.75 | DPP4 (0.42) | DPP4 | |
| SCHEMBL20187562 | 0.74 | MEN1 (0.33) | EPHX1S1PR1GAADPP4 | |
| SCHEMBL6507996 | 0.73 | NFKB1 (0.32) | — | |
| SCHEMBL27780868 | 0.73 | ELANE (0.35) | EPHX1BTKS1PR1 | |
| SCHEMBL13269590 | 0.73 | DGAT1 (0.33) | — | |
| SCHEMBL574102 | 0.73 | BTK (0.36) | EPHX1BTKGAADPP4 | |
| SCHEMBL11282770 | 0.72 | DPP4 (0.36) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005075426-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS THEREOF | GLENMARK PHARMACEUTICALS LTD. (US) | 2005-08-18 | — | — | WO | claimed |