Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16573 | 0.89 | — | — | |
| SCHEMBL21772349 | 0.89 | TSHR (0.69) | TSHRTHRBALDH1A1TDP1POLB | |
| Dimethylamine SCHEMBL1033277 | 0.88 | TSHR (0.62) | TSHRTHRBALDH1A1TDP1POLB | |
| Hydrochloric Acid SCHEMBL31358617 | 0.87 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| Hydrogen Sulfide SCHEMBL6879353 | 0.87 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1514196 | 0.87 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL6879356 | 0.87 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| Hydrochloric Acid SCHEMBL8572537 | 0.87 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| Hydrochloric Acid SCHEMBL28868459 | 0.87 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL31029924 | 0.87 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484785-B | Preparation method of amphiphilic polymer antifogging coating based on zwitterion | 东华大学 | 2021-09-21 | — | — | CN | claimed |
| CN-111484785-A | Preparation method of amphiphilic polymer antifogging coating based on zwitterion | 东华大学 | 2020-08-04 | — | — | CN | claimed |
| CN-107266624-B | Water-absorbent resin, preparation method and application thereof | 海信视像科技股份有限公司 | 2020-06-19 | — | — | CN | claimed |
| CN-115162044-B | Method for producing paper or board | 索理思科技开曼公司 | 2024-02-23 | — | — | CN | disclosed |
| US-11680371-B2 | Method for producing multi-layer paper | SOLENIS TECHNOLOGIES, L.P. (US) | 2023-06-20 | — | — | US | disclosed |
| CN-116056571-A | Agrochemical formulations | 巴斯夫欧洲公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-113039224-B | Method for producing paper or board | 索理思科技开曼公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-113039223-B | Method for hydrolyzing polymer | 索理思科技开曼公司（KY） | 2023-01-13 | — | — | CN | disclosed |
| CN-111511986-B | Method for producing paper or paperboard | 索理思科技开曼公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115162044-A | Method for producing paper or paperboard | 索理思科技开曼公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-114901467-A | Heat resistant shrinkable adhesive film | 3M创新有限公司 | 2022-08-12 | — | — | CN | disclosed |
| EP-3697963-A1 | METHOD FOR PRODUCING MULTI-LAYER PAPER | Solenis Technologies Cayman, L.P. (KY) | 2020-08-26 | — | — | EP | disclosed |
| EP-3697964-A1 | METHOD FOR PRODUCING SINGLE-LAYER OR MULTI-LAYER PAPER | Solenis Technologies Cayman, L.P. (KY) | 2020-08-26 | — | — | EP | disclosed |
| CN-111566284-A | Method for producing single-ply or multi-ply paper | 索理思科技开曼公司 | 2020-08-21 | — | — | CN | disclosed |
| EP-3695051-A1 | METHOD FOR MANUFACTURING PAPER OR CARDBOARD | Solenis Technologies Cayman, L.P. (KY) | 2020-08-19 | — | — | EP | disclosed |
| CN-111511986-A | Method for producing paper or paperboard | 索理思科技开曼公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111484785-A | Preparation method of amphiphilic polymer antifogging coating based on zwitterion | 东华大学 | 2020-08-04 | — | — | CN | disclosed |
| EP-1500670-A1 | CROSSLINKED POLYMER, FINE POLYMER PARTICLE, AND PROCESS FOR PRODUCING THESE | Japan Science and Technology Agency (JP) | 2005-01-26 | — | — | EP | disclosed |
| US-6601961-B1 | Light guide plate and process for producing the same, surface light source equipment and liquid crystal display | DAI NIPPON PRINTING CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| US-20020181111-A1 | Optical sheet | KEIWA KABUSHIKI KAISHA, A JAPANESE CORPORATION (JP) | 2002-12-05 | — | — | US | disclosed |